Nasal Mucosal Absorption Mechanics and Why Intranasal GLP-1 Outpaces Oral Bioavailability Ceilings
Intranasal delivery bypasses digestive degradation that limits oral GLP-1 bioavailability.
Daniel Ngô
Section
Drug Delivery
8 stories in Drug Delivery.
Pulmonary Inhalation as a Peptide Delivery Route for Systemic Indications
Inhaled peptides face barriers that make systemic delivery harder than lung anatomy suggests.
Daniel Ngô
Long-Acting Peptide Depot Formulations as an Injection-Reduction Strategy
Fewer injections come with trade-offs in needle size and drug stability.
Cecilia Brandt-Kowalski
Blood-Brain Barrier Crossing Strategies for Large Biologic Molecules
Engineers are finding multiple routes to get large drug molecules into the brain.
Priya Subramaniam
Peptide Absorption Enhancers in Non-Injectable Formulations
Three strategies overcome the gut barriers that keep peptide drugs injectable.
Daniel Ngô
Transdermal Peptide Delivery Technologies and Their GLP-1 Applicability
Skin's lipid barrier makes GLP-1 patches fundamentally harder than injection, and the data prove it.
Priya Subramaniam
Subcutaneous Auto-Injector Design and Its Adherence Ceiling
The handheld auto-injector hits its limits with larger, thicker drugs.
Priya Subramaniam
Oral GLP-1 Delivery Platforms and the Bioavailability Problem
Oral GLP-1s work around fundamental biology by accepting near-total losses at the gut barrier.
Daniel Ngô